Table 1 The 25 highest ranked pathways based on z score
Pathway | Positive (r) | Measured (n) | Total | % | z Score |
|---|---|---|---|---|---|
Fatty acid biosynthesis | 15 | 19 | 22 | 78.95 | 5.91 |
Fatty acid beta oxidation 1 | 14 | 23 | 27 | 60.87 | 4.42 |
Muscle, fat and connective tissue specific genes | 16 | 28 | 55 | 57.14 | 4.41 |
Pentose phosphate pathway | 6 | 7 | 8 | 85.71 | 4.01 |
Beta oxidation meta MAPP | 15 | 28 | 32 | 53.57 | 3.95 |
Mitochondrial LC-fatty acid beta-oxidation | 9 | 15 | 16 | 60.00 | 3.49 |
Genes specific to internal organs | 30 | 79 | 202 | 37.97 | 3.32 |
Genes specific to blood and lymph tissue | 7 | 11 | 17 | 63.64 | 3.28 |
Glutathione metabolism | 9 | 16 | 38 | 56.25 | 3.24 |
Irinotecan pathway | 5 | 7 | 13 | 71.43 | 3.11 |
Fatty acid beta oxidation 2 | 4 | 6 | 6 | 66.67 | 2.6 |
Genes specific to blood and lymph tissue | 9 | 21 | 40 | 42.86 | 2.24 |
Myometrial relaxation and contraction pathways | 33 | 105 | 161 | 31.43 | 2.22 |
Alanine and aspartate metabolism | 4 | 7 | 40 | 57.14 | 2.2 |
Inflammatory response pathway | 10 | 25 | 41 | 40.00 | 2.11 |
Cholesterol biosynthesis | 5 | 10 | 15 | 50.00 | 2.09 |
Circadian exercise | 13 | 35 | 49 | 37.14 | 2.09 |
Triacylglyceride synthesis | 8 | 19 | 25 | 42.11 | 2.06 |
Mouse insulin signaling | 36 | 121 | 160 | 29.75 | 1.94 |
Oxidative stress | 9 | 23 | 29 | 39.13 | 1.92 |
G Protein signaling pathways | 20 | 61 | 87 | 32.79 | 1.89 |
Tryptophan metabolism | 11 | 30 | 87 | 36.67 | 1.87 |
Fatty acid beta oxidation 3 | 4 | 8 | 8 | 50.00 | 1.87 |
Striated muscle contraction | 8 | 21 | 45 | 38.10 | 1.72 |
Nuclear receptors in lipid metabolism and toxicity | 7 | 18 | 34 | 38.89 | 1.67 |