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Table 1 Changes in subject characteristics at the end of 8-week low-calorie diet compared to baseline, and at the end of 6-month ad libitum diet compared to the end of 8-week low-calorie diet

From: Variation in extracellular matrix genes is associated with weight regain after weight loss in a sex-specific manner

 

Baseline

After 8-week LCD

After 6-month ad libitum diet

Male

Female

Male

Female

Male

Female

WM

WR

WM

WR

WM

WR

WM

WR

WM

WR

WM

WR

n

59

100

135

175

59

100

135

175

59

100

135

175

Age (year)

43 ± 6

43 ± 6

41 ± 7

42 ± 6

        

Weight (kg)

111.3 ± 18.5

107.9 ± 17.1

97.3 ± 18.3

92.1 ± 13.1

97.7 ± 17.3*

95.3 ± 15.0*

86.3 ± 16.6*

82.6 ± 12*

93.5 ± 17.5#

99.8 ± 15.7#

81.6 ± 15.1#

86.2 ± 12.6#

BMI (kg/m2)

35.4 ± 4.9

33.4 ± 4.6

35.1 ± 5.4

33.5 ± 4.4

31.1 ± 4.6*

29.6 ± 4.1*

31.1 ± 4.8*

30.1 ± 4.0*

29.8 ± 4.7#

30.9 ± 4.3#

29.5 ± 4.5#

31.4 ± 4.2#

WC (cm)

117.4 ± 12.9

111.9 ± 11.8

104.9 ± 13.6

102.3 ± 10.4

105.4 ± 12.7*

100.5 ± 11.5*

95.2 ± 12.3*

93.6 ± 10.1*

101 ± 12.4#

104.5 ± 12.0#

91.8 ± 12.2#

96.4 ± 10.1#

Fat mass (kg)

39.6 ± 13.4

34.1 ± 10.7

44 ± 12

40.8 ± 9.3

30.4 ± 10.6*

26.7 ± 10.1*

35.3 ± 10.9*

33.8 ± 9.3*

25.3 ± 10.6#

28.4 ± 10.3#

30.5 ± 9.4#

35.6 ± 9.2#

WMS

        

−0.33 ± 0.34

0.38 ± 0.25

−0.42 ± 0.39

0.40 ± 0.31

  1. Values are mean ± SD. Subjects are divided into four groups: male weight maintainers (WM, n = 59), weight regainers (WR, n = 100) and female WM (n = 135) and WR (n = 175). Weight maintenance score (WMS) is calculated at the end of the 6-month ad libitum diet: (weight after 6-month ad libitum diet − weight after LCD)/(weight at baseline − weight after LCD)
  2. WC waist circumference, LCD low-calorie diet, WMS weight maintenance score
  3. P < 0.001 change from baseline versus after 8-week LCD with dependant t test per group
  4. # P < 0.001 change from after 8-week LCD versus after 6-month ad libitum diet with dependent t test per group