Table 2 Association between SNPs in WNT-associated genes and type 2 diabetes and related traits in MDCS

TCF7L2 rs7903146

1.33 (1.25–1.40)

1 × 10⁻²³

0.04 (0.02)

0.03

0.16 (1.05)

0.82

0.02 (0.01)

0.04

TCF7L2 rs12255372

1.24 (1.17–1.31)

9 × 10⁻¹⁴

0.03 (0.02)

0.15

−0.73 (1.07)

0.79

0.02 (0.01)

0.07

HHEX rs1111875

1.06 (1.01–1.12)

0.03

−0.02 (0.02)

0.20

−3.07 (0.99)

0.016

0.01 (0.01)

0.31

HNF1A rs7957197

1.12 (1.05–1.20)

0.001

0.04 (0.02)

0.04

1.11 (1.23)

0.54

0.01 (0.01)

0.30

NOTCH2 rs10923931

0.99 (0.91–1.09)

0.90

0.04 (0.03)

0.19

−0.14 (1.73)

0.69

0.02 (0.02)

0.35

TLE4 rs13292136

1.03 (0.94–1.12)

0.60

−7 × 10⁻⁰⁵ (0.03)

1.00

1.71 (1.72)

0.40

0.02 (0.02)

0.30

ZBED3 rs4457053

1.01 (0.96–1.08)

0.64

0.01 (0.02)

0.44

−1.41 (1.14)

0.22

0.02 (0.01)

0.04

PPARG rs1801282

1.08 (1.00–1.16)

0.051

0.03 (0.02)

0.24

1.16 (1.38)

0.42

−0.002 (0.01)

0.88

PPARG rs13081389

1.00 (0.91–1.11)

0.97

0.03 (0.03)

0.35

1.67 (1.79)

0.33

0.01 (0.02)

0.68