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Table 5 The differentially expressed genes in adipocytes of finishing pigs treated with db-cAMP

From: Dibutyryl-cAMP affecting fat deposition of finishing pigs by decreasing the inflammatory system related to insulin sensitive or lipolysis

Gene ID

Gene name

Gene description

P value

Fold change

Up-regulated

396739

SAL1

salivary lipocalin

0.0025

22.14

407247

LHCGR

luteinizing hormone/choriogonadotropin receptor

0.044

5.18

641359

SULT2A1

sulfotransferase family, cytosolic, 2A, dehydro- epiandrosterone (DHEA)-preferring, member 1

0.0412

4.37

396597

STAR

steroidogenic acute regulatory protein

0.0043

4.14

403149

CYP2A19

cytochrome P450 2A19

0.0096

3.40

397290

HOXD10A

homeobox protein A10

0.0209

2.87

100124377

SBAB-707F1.10

solute carrier family 44, member 4

0.0353

2.58

397670

RH

Rh protein

0.0444

2.56

733668

DIRAS3

DIRAS family, GTP-binding RAS-like 3

0.0036

2.41

397324

ACACA

acetyl-Coenzyme A carboxylase alpha

0.0252

2.40

396861

LCN1

lipocalin 1 (tear prealbumin)

0.0062

2.29

100048933

ZFAND5

zinc finger, AN1-type domain 5

0.0113

2.25

100216478

TEF1

transcriptional enhancer factor 1

0.0200

2.19

414420

RPS28

ribosomal protein S28

0.0228

2.10

Down-regulated

100157574

LOC100157574

similar to family with sequence similarity 49, member B

0.0022

0.50

100156398

LOC100156398

mini-chromosome maintenance complex component 4

0.0333

0.50

100154512

LOC100154512

similar to tripartite motif-containing 38

0.046

0.49

397330

XPO1

exportin 1 (CRM1 homolog, yeast)

0.0159

0.49

396599

MCSF ALPHA

macrophage colony stimulating factor alpha

0.0219

0.49

733579

LOC733579

tripartite motif protein TRIM5

0.0241

0.49

396655

STAT1

signal transducer and activator of transcription 1

0.0379

0.49

397177

DUOX1

dual oxidase 1

0.0234

0.48

100157208

LOC100157208

similar to Tectonic-3

0.0314

0.48

397222

MEOX2

mesenchyme homeobox 2

0.0095

0.48

100125540

SYK

spleen tyrosine kinase

0.0183

0.48

397108

GP91-PHOX

NADPH oxidase heavy chain subunit

0.0339

0.48

100154251

LOC100154251

similar to pleckstrin 2

0.0409

0.47

100048944

CPEB1

cytoplasmic polyadenylation element binding protein 1

0.0375

0.47

100158101

LOC100158101

similar to Rho GTPase-activating protein 30

0.0053

0.47

100048955

C5AR1

complement component 5a receptor 1

0.0121

0.47

100037274

TAF4B

TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105 kDa

0.0089

0.46

397041

LGALS4

lectin, galactoside-binding, soluble, 4

0.0439

0.46

100049698

SNCAIP

synuclein, alpha interacting protein

0.0078

0.45

595128

OAS2

2'-5'-oligoadenylate synthetase 2, 69/71 kDa

0.0401

0.453

397422

CCL2

chemokine (C-C motif) ligand 2

0.0181

0.45

387287

HCRTR1

hypocretin (orexin) receptor 1

0.0387

0.45

100124526

CD1D

CD1d molecule

0.0189

0.45

397271

AIF1

allograft inflammatory factor 1

0.0132

0.44

396935

PCCB

propionyl Coenzyme A carboxylase, beta polypeptide

0.0326

0.44

733649

TAP1

transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

0.0419

0.44

100156191

LOC100156191

zygote arrest 1-like protein

0.0402

0.44

414912

PU.1

transcription factor PU.1

0.0044

0.43

100157355

LOC100157355

similar to spindle and KT associated 1

0.0325

0.43

404704

CD4

CD4 molecule

0.0029

0.43

100126851

SERPINB9

serpin peptidase inhibitor, clade B (ovalbumin), member 9

0.0464

0.42

396723

DDX58

DEAD (Asp-Glu-Ala-Asp) box polypeptide 58

0.0049

0.42

396943

ITGB2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

0.0088

0.41

397141

NPL

N-acetylneuraminate pyruvate lyase

0.0157

0.40

100037296

TLR7

toll-like receptor 7

0.0053

0.40

100048946

RNASEL

Ribonuclease-L(2',5'-oligoisoadenylate-synthetase- dependent)

0.0105

0.40

100048958

GNA14

guanine nucleotide binding protein (G protein), alpha 14

0.0486

0.40

397441

CD86

CD86 molecule

0.0208

0.40

399500

IL6

interleukin 6 (interferon, beta 2)

0.0176

0.39

397590

PGHS-2

prostaglandin G/H synthase-2

0.024

0.38

100049665

KRT2

keratin 2

0.019

0.38

445460

C1QC

complement component 1, q subcomponent, C chain

0.0045

0.38

100156254

LOC100156254

similar to Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P)

0.0435

0.38

100155269

LOC100155269

similar to lymphocyte antigen 9

0.0131

0.37

396900

AMCF-II

alveolar macrophage-derived chemotactic factor-II

0.0494

0.37

404772

GEM

GTP binding protein overexpressed in skeletal muscle

0.0291

0.36

397414

UF

uteroferrin

0.0066

0.36

100153090

LOC100153090

similar to Cathepsin S

0.0411

0.36

414373

CCR3

chemokine (C-C motif) receptor 3

0.0179

0.3

100152784

LOC100152784

Vascular non-inflammatory molecule 3 precursor (Vanin-3)

0.0392

0.35

399541

TLR4

toll-like receptor 4

0.0474

0.35

606745

LOC606745

A2b adenosine receptor

0.0159

0.35

100049673

HPS3

Hermansky-Pudlak syndrome 3

0.038

0.35

396624

OX40L

OX40L protein

0.0323

0.35

414374

CCR1

chemokine (C-C motif) receptor 1

0.0196

0.34

100152550

LOC100152550

similar to EF-hand domain (C-terminal) containing 1

0.038

0.34

503658

ENPP2

ectonucleotide pyrophosphatase/phosphodiesterase 2

0.0481

0.33

397079

CECR1

cat eye syndrome chromosome region, candidate 1

0.0057

0.33

396880

IL8

interleukin 8

0.0091

0.32

396985

PLAU

plasminogen activator

0.0474

0.32

100154994

LOC100154994

similar to serine proteinase inhibitor, clade B, member 10

0.0192

0.31

574057

PDCD1LG2

programmed cell death 1 ligand 2

0.0178

0.30

396726

FASLG

Fas ligand (TNF superfamily, member 6)

0.0261

0.30

414904

CXCL2

chemokine (C-X-C motif) ligand 2

0.0093

0.30

100156373

LOC100156373

similar to villin 1

0.0067

0.28

397373

MYO7A

myosin VIIA

0.0473

0.27

397102

AMBN

ameloblastin

0.0329

0.19

100049669

GPNMB

glycoprotein (transmembrane) nmb

0.0447

0.18

396662

CD2

CD2 molecule

0.0212

0.16

100135044

SBAB-591C4.5

MHC class II, DQ alpha

0.0027

0.09