Gastric infusion of short-chain fatty acids can improve intestinal barrier function in weaned piglets

Genes & Nutrition

Table 4 Effect of gastric infusion of SCFA on apoptosis and cell cycle in jejunum and colon of weaned piglets (%)

Items	Control	S1	S2	SEM	P value
Jejunum
Early apoptotic cells	0.322	0.074	0.003	0.107	0.168
Late apoptotic cells	0.975^a	0.268^ab	0.007^b	0.210	0.042
Total apoptotic cells	1.218	0.334	0.009	0.313	0.063
G0G1 phase cells	73.388^a	63.092^b	53.642^c	1.969	< 0.001
S phase cells	18.108	21.897	29.512	3.569	0.119
G2M phase cells	8.502	15.015	16.848	2.536	0.096
PI	26.61^c	36.911^b	46.359^a	1.969	< 0.001
Colon
Early apoptotic cells	4.053	3.358	1.700	1.354	0.493
Late apoptotic cells	20.975^a	7.220^b	3.155^b	2.032	0.002
Total apoptotic cells	26.219^a	10.578^b	4.855^b	1.789	0.001
G0G1 phase cells	62.957^a	55.125^b	49.610^b	1.855	0.002
S phase cells	30.163	33.785	37.463	2.261	0.123
G2M phase cells	6.883	11.093	12.922	2.411	0.241
PI	37.045^b	44.877^a	50.388^a	1.855	0.002

S1, pigs treated with SCFA (acetic, propionic and butyric acids; 20.04, 7.71, and 4.89 mM respectively); S2, pigs treated with SCFA (acetic, propionic, and butyric acids; 40.08, 15.41, and 9.78 mM respectively)
PI = (S + G2M)/(G0G1 + S + G2M) × 100%
^{a, b}Within a row, means without a common superscript differ (P < 0.05)

ISSN: 1865-3499