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Table 2 Characteristics of the clinical metabotypes

From: Associations between dietary intake and glucose tolerance in clinical and metabolomics-based metabotypes

 

Favorable clinical metabotype (n = 99)*

Unfavorable clinical metabotype (n = 104)**

n (%)

 Men

31 (31.3)

39 (37.5)

 Statin users

5 (5.1)

24 (23.1)

 Anti-inflammatory drug users

3 (3)

4 (3.8)

 Premenopausal women

48 (71)

18 (28)

 Women using hormonal contraceptives

27 (40)

5 (8)

Mean (SD)

 Age (years)

44 (12)

55 (10)

 BMI (kg/m2)

30.9 (5.1)

33.3 (4.7)

 Waist circumference (cm)

101.2 (14.0)

111.9 (12.0)

 HbA1c (mmol/mol)

27 (14)

33 (16)

 Total-C (mmol/L)

5.0 (0.9)

5.1 (1.0)

 LDL-C (mmol/L)

3.3 (0.8)

3.5 (1.0)

Median (IQR)

 HDL-C (mmol/L)

1.4 (0.5)

1.3 (0.4)

 Triglycerides (mmol/L)

1.15 (0.56)

1.46 (1.02)

 Lp(a) (mg/L)

316 (498)

202 (425)

 Fasting glucose (mmol/L)

4.9 (0.4)

5.8 (0.8)

 Insulin (pmol/L)

61 (42)

100 (77)

 2-h glucose (mmol/L)

4.7 (1.4)

6.6 (2.6)

 Systolic BP (mmHg)

116 (14)

124 (21)

 Diastolic BP (mmHg)

68 (12)

72 (13)

 CRP (mg/L)

2.1 (3.1)

3.8 (5.1)

  1. BMI, body mass index; HbA1c, glycated haemoglobin; C, cholesterol; LDL, low-density lipoprotein; HDL, hgh-density lipoprotein; Lp(a), lipoprotein a; BP, blood pressure; CRP, C-reactive protein
  2. *Age, n = 96; BMI and waist circumference, n = 98; Lp(a), n = 50; 2-h glucose, n = 97
  3. **Age and BMI, n = 103; fat mass, n = 98; LDL-C and HDL-C, n = 102; Lp(a), n = 66