Skip to main content

Table 3 Genistein effects on HMG-CoA reductase gene expression in DLD-1 cells

From: Effect of genistein on cholesterol metabolism-related genes in a colon cancer cell line

Genistein

24 h

48 h

Control

1.04 ± 0.03

1.02 ± 0.01

0.01 μM

1.03 ± 0.01

0.8 ± 0.01

1 μM

1.02 ± 0.01

0.6 ± 0.02*

10 μM

0.92 ± 0.04

0.5 ± 0.01*

50 μM

0.8 ± 0.02

0.6 ± 0.05*

  1. Data displayed as mean ± SE of number molecules mRNA HMG-CoA reductase/number molecules mRNA β-actin. P value was determined by one-way analysis with Dunnett’s post-test. *P < 0.05 versus control. Results derived from triplicate cultures set up for each phytoestrogen concentration and for control, and each experiment was repeated four times
Back to article page

Genes & Nutrition

ISSN: 1865-3499

Contact us