Fig. 2

The tenets of Nutrigenomics are essentially based on the concepts that diet can be an important risk factor for a wide number of diseases and that dietary compounds can directly or indirectly interact with the genome by altering gene expression. So, the individual genetic factor can influence the balance between physiological and pathological condition determined by diet and several diet-regulated genes can play a fundamental role in the incidence and progression of many chronic diseases. For these reasons, a personalized diet on the basis of nutritional status and genotype can be very helpful in preventing and curing human diseases, including cancer. The eventual implementation of these concepts in every-day clinical practice promises to revolutionize the preventive and therapeutic approach to many diseases thereby reducing the need for conventional pharmaceutical therapy