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Table 2 Mice were fed either the basal diet or diets containing 500 mg/kg of either BC or LY for 4 weeks

From: Effects of dietary carotenoids on mouse lung genomic profiles and their modulatory effects on short-term cigarette smoke exposures

 

Control diet

β-carotene diet

Lycopene diet

Plasma (nM)

 β-carotene

<3.7

50.3 ± 13.7a

<3.7

 Lycopene

<3.7

<3.7

179.9 ± 16.2a

Lung (nmol/kg)

 β-carotene

<60

139.6 ± 11.6a

<60

 Lycopene

<60

<60

308.1 ± 62.5a

  1. Concentration of BC and LY were measured in plasma (nM) or lung (nmol/kg) at time of sacrifice
  2. aAll data are given as mean ± SEM, n = 4. BC and LY were below the limit of detection in plasma and lung of mice fed the basal diet. Four weeks of dietary supplementation resulted in a large and significant (P < 0.001) increase in plasma and lung concentrations of the two CARs