Skip to main content

Table 1 Comparison of microarray changes in relative gene expression (between Matrigel plug cells from mice fed with a standard diet (ST) and matrigel plug cells from mice fed with a high-fat diet (HF)) in RXRα-deficient mice (hRXRa ko) and WT mice

From: Hepatocyte RXR alpha deletion in mice leads to inhibition of angiogenesis

 

WT

hRXRa ko

Gene symbol

HF vs ST

HF vs ST

Angiogenesis

 Kdr

nc

−1.87a

 Pdgfrb

nc

−1.52a

 Nos3

nc

−2.64a

Apoptosis

 Prf1

−4.29a

2.14b

 Gzmb

−5.66a

9.85b

 Bcl2l11

−1.87a

1.41b

 Nfkbie

−2.14a

4b

 Nfkb1

−1.32a

1.52b

 Nfkbia

−1.52a

1.32b

 Tnfrsf21

−1.52a

2b

 Tnfrsf1b

−2.14a

1.87b

 Casp3

−1.62a

nc

 Casp6

−1.74a

nc

 Birc5

nc

−1.41a

 Birc4

nc

−1.52a

Adipogenesis

 Cebpb

−3.48a

1.74b

 Srebf1

nc

1.74b

 Adipoq

3.73b

−6.96a

 Retn

nc

−6.06a

 Adn

7.46b

−13a

 Fabp4

1.62b

−4.92a

 Lpl

3.03b

nc

  1. nc no change
  2. aDown-regulated genes
  3. bUp-regulated genes