Fig. 4
From: Effect of body fat distribution on the transcription response to dietary fat interventions
Correlation of MICB (MHC class I polypeptide-related sequence B) and ADIPOQ (adiponectin) gene expression ratios with WHR. MICB (MHC class I polypeptide-related sequence B) and ADIPOQ (adiponectin) are examples of genes with log2(MCT/PUFA) expression ratios significantly positively and negatively correlated (r = 0.87, p = 0.0005 and r = –0.78, p = 0.004, respectively) to WHR values in 11 subjects. MICB is stress-induced protein involved in immune response, while low adiponectin expression is an acknowledged marker for obesity-associated disorders. Subjects with increased WHR (upper body obesity) have induced expression of MICB and repressed expression of ADIPOQ in their adipose tissues when consuming MCT versus PUFA diet