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Fig. 2 | Genes & Nutrition

Fig. 2

From: CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction

Fig. 2

The CYP2E1 inhibitor, chlormethiazole, protects against LPS plus pyrazole toxicity and oxidative/nitrosative stress in mice. Sal Saline-treated, P+L pyrazole plus LPS treated, C+P+L CMZ plus pyrazole plus LPS treated. a ALT/AST levels. b histopathology, c 4-HNE adducts, d 3-NT adducts. For b, c and d, panels a are the saline treated; panels b are the LPS plus pyrazole treated; panels c refer to the CMZ plus LPS plus pyrazole treated

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Genes & Nutrition

ISSN: 1865-3499

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