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Fig. 3 | Genes & Nutrition

Fig. 3

From: CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction

Fig. 3

LPS plus pyrazole toxicity is lowered in CYP2E1 knockout mice. a ALT/AST levels, b histopathology, a LPS plus pyrazole treated CYP2E1 knockout mice, b LPS plus pyrazole treated wild type control. c TUNEL staining for DNA fragmentation; a the CYP2E1 null mice and b wild type mice. d Immunoblot for CYP2E1 levels in wild type female or male mice (WTF, WTM) or male and female CYP2E1 knockout mice (KOM, KOF)

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Genes & Nutrition

ISSN: 1865-3499

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