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Table 3 Ethanol-induced defects in clathrin-mediated endocytosis

From: Alcohol consumption impairs hepatic protein trafficking: mechanisms and consequences

Protein

EtOH exposure

System

References

ASGP

Acute & Chronic

Isolated hepatocytes, intact perfused rat liver, HAD

[11, 13, 14, 54, 76, 92, 102]

ASGP-R

Acute & Chronic

Isolated hepatocytes, WIF-B

[35, 54, 102]

Iron via transferrin

Acute

Isolated hepatocytes

[4]

Transferrin receptor

Chronic

WIF-B

[24]

Polymeric IgA receptor

Chronic

WIF-B

[24]

Chylomicron remnants

Chronic

Isolated hepatocytes

[39]

TGF-α

Chronic

Isolated hepatocytes

[99]

TNF-α

Chronic

Isolated hepatocytes

[99]

IL-6

Chronic

Isolated hepatocytes

[99]

EGF

Chronic

Isolated hepatocytes

[10, 18, 63]

Insulin

Chronic

Isolated hepatocytes, humans

[62, 71, 91]

Growth hormone

Acute & chronic

Rat liver slices, humans

[17, 113]

Glucagon

Chronic

Rat liver plasma membranes

[41]

Aminopeptidase-N

Chronic

WIF-B

[35]

Dipeptidyl peptidase IV

Chronic

WIF-B

[24]

Hemagglutinin

Chronic

WIF-B

[24]