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Table 4 Differentially expressed genes between tabw2 and control mice in liver and adipose tissue (fat) that are located within the congenic interval on chromosome 6

From: Gene expression profiles of a mouse congenic strain carrying an obesity susceptibility QTL under obesigenic diets

Probe set ID

Symbol

Gene name

Mb

Tissue

Fold

1441727_s_at

Zfp467

Zinc finger protein 467

48.4

Fat

−1.85

1434043_a_at

Repinl

Replication initiator 1

48.5

Fat

−1.73

1424375_s_at

Gimap4

GTPase, IMAP family member 4

48.6

Fat

1.64

1420365_a_at

Hnrpa2b1

Heterogeneous nuclear ribonucleoprotein A2/B1

51.4

Liver

−1.16

1428922_at

1200009O22Rik

RIKEN cDNA 1200009O22 gene

53.8

Fat

−2.20

1434016_at

Znrf2

Zinc and ring finger 2

54.8

Fat

1.77

1444735_at

   

Liver

−1.28

1423784_at

Gars

Glycyl-tRNA synthetase

55.0

Liver

−1.26

1418697_at

Inmt

Indolethylamine N-methyltransferase

55.1

Fat

2.26

1418656_at

Lsm5

LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)

56.7

Liver

−1.23

1457023_at

5830411G16Rik

Riken cDNA 5830411G16 gene

56.7

Liver

1.83

1432026_a_at

Herc5

Hect domain and RLD 5

57.4

Liver

1.32

1429194_at

Tigd2

Tigger transposable element derived 2

59.2

Liver

−1.41

1449519_at

Gadd45a

Growth arrest and DNA-damage-inducible 45 alpha

67.0

Liver

−1.74

1427860_at

LOC100047162

Similar to Ig kappa chain V–V region MPC11 precursor

70.4

Fat

1.54

1425335_at

Cd8a

CD8 antigen, alpha chain

71.3

Fat

1.96

1443830_x_at

Rnf103

Ring finger protein 103

71.5

Liver

−1.39

1420289_at

T25656

Expressed sequence T25656

71.6

Liver

1.11

1424716_at

Restsat

Retinol saturase (all trans retinol 13, 14 reductase)

72.5

Liver

−1.58

1450117_at

Tcf3

Transcription factor 3

72.6

Fat

−1.64

1448895_a_at

Ctnna2

Catenin (cadherin associated protein), alpha 2

76.8

Liver

1.38

1432286_at

Pole4

Polymerase (DNA-directed), epsilon 4 (p12 subunit)

82.6

Liver

1.26

1423371_at

   

Fat

3.11

1436618_at

Sfxn5

Sideroflexin 5

85.2

Liver

−1.67

1432969_at

4933423K11Rik

RIKEN cDNA 4933423K11 gene

85.3

Liver

1.09

1418013_at

Cml1

Camello-like 1

85.9

Fat

−1.51

1447277_s_at

Pcyox1

Prenylcysteine oxidase 1

86.3

Liver

−1.27

1418229_s_at

Nfu1

NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)

87.0

Liver

−1.32

1453132_a_at

Gkn2

Gastrokine2

87.3

Liver

1.38

1459728_at

Isy1

ISY1 splicing factor homolog (S. cerevisiae)

87.8

Fat

−2.46

    

Liver

−1.35

1416244_a_at

Cnbp

Cellular nucleic acid binding protein

87.8

Liver

−1.17

1416585_at

Ruvbl1

RuvB-like protein 1

88.4

Liver

−1.30

1442560_at

Mgll

Monoglyceride lipase

88.7

Liver

−2.01

1453462_at

Chst13

Carbohydrate (chondroitin 4) sulfotransferase 13

90.3

Liver

−2.92

1451229_at

Hdac11

Histone deacetylase 11

91.1

Liver

−1.27

1456879_at

C130022K22Rik

RIKEN cDNA C130022K22 gene

91.8

Liver

−1.50

1416911_a_at

6330407G11Rik

RIKEN cDNA 6330407G11 gene

92.0

Liver

−2.10

1449194_at

Mrps25

Mitochondrial ribosomal protein S25

92.1

Liver

−1.24

1439933_at

B430316J06Rik

RIKEN cDNA B430316J06 gene

93.9

Liver

−1.74

1443231_at

AW544 786

Expressed sequence tag

94.2

Fat

−2.22

1433671_at

A130022J15Rik

RIKEN cDNA A130022J15 gene

97.1

Liver

1.49

1452123_s_at

Frmd4b

FERM domain containing 4B

97.2

Liver

−1.83

1426594_at

   

Fat

1.34

1421111_at

Rybp

RING1 and YY1 binding protein

100.1

Liver

1.18

1428137_at

Arl8b

ADP-ribosylation factor-like 8b

108.7

Liver

−1.50

1443954_at

Rad18

RAD18 homolog (S. cerevisiae)

112.6

Fat

1.27

1423189_at

6720456B07Rik

RIKEN cDNA 6720456B07 gene

113.5

Liver

−1.37

1444806_at

AK054191

Expressed sequence tag

113.5

Fat

1.98

1447147_at

AI747732

Expressed sequence tag

114.8

Fat

3.46

1440028_at

4631423B10Rik

RIKEN cDNA 4631423B10 gene

114.8

Fat

−1.70

1437677_at

AI449595

Expressed sequence tag

114.9

Liver

1.11

1416078_s_at

Rafl

v-Raf-1 leukemia viral oncogene 1

115.5

Liver

−1.37

1440384_at

Tmccl

Transmembrane and coiled-coil domains 1

115.9

Liver

−1.94

    

Fat

−1.88

1417574_at

Cxcl12

Chemokine (C-X-C motif) ligand 12

117.1

Fat

2.25

1436359_at

Ret

Ret proto-oncogene

118.1

Fat

−3.46

1422602_a_at

Wnt5b

Wingless-related MMTV integration site 5B

119.3

Liver

1.19

1417407_at

Fbxl14

F-box and leucine-rich repeat protein 14

119.4

Liver

−1.50

1424247_at

Ercl

ELKS/RAB6-interacting/CAST family member 1

119.5

Fat

−1.71

1434221_at

BC030863

cDNA sequence BC030863

120.8

Liver

−1.20

1425951_a_at

Clec4n

C-type lectin domain family 4, member n

123.1

Fat

1.68

1426770_at

Pex5

Peroxisome biogenesis factor 5

124.3

Liver

−1.33

1422106_a_at

Spsb2

SplA/ryanodine receptor domain and SOCS box containing 2

124.7

Fat

−1.12

1455215_at

C530028O21Rik

RIKEN cDNA C530028O21 gene

124.9

Fat

−3.92

1455785_at

Kcnal

Potassium voltage-gated channel, shaker-related subfamily, member 1

126.5

Fat

1.26

1448229_s_at

Ccnd2

Cyclin D2

127.0

Fat

4.67

1434745_at

   

Liver

−1.69

1460245_at

Klrdl

Killer cell lectin-like receptor, subfamily D, member 1

129.5

Fat

3.39

1446155_at

AK078025

Expressed sequence tag

133.0

Fat

2.32

1415968_a_at

Kap

Kidney androgen-regulated protein

133.7

Fat

−2.87

1440982_at

BB209400

Expressed sequence tag

134.0

Fat

−1.23

1451022_at

Lrp6

Low density lipoprotein receptor-related protein 6

134.4

Fat

−1.92

    

Liver

−1.29

1435085_at

Crebl2

CAMP responsive element binding protein-like 2

134.8

Liver

−1.39

1434045_at

Cdkn1b

Cyclin-dependent kinase inhibitor 1B

134.8

Liver

−1.89

1426454_at

Arhgdib

Rho, GDP dissociation inhibitor (GDI) beta

136.8

Liver

1.58

  1. Genes in bold are present in the top 50 genes with the largest fold change between tabw2 and control mice
  2. Mb, mega-base; ‘−’ indicates up-regulation and ‘no sign’ indicates down-regulation in tabw2 mice compared to control mice