Gene/SNP | Colon cancer | Rectal cancer | ||||
---|---|---|---|---|---|---|
Case/cont | ORa (95% CI) | ORb (95% CI) | Case/cont | ORa (95% CI) | ORb (95% CI) | |
SOD2 | ||||||
RS4880 | ||||||
AA | 126/265 | 1.0 | 1.0 | 114/265 | 1.0 | 1.0 |
GA + GG | 29/56 | 1.14 (0.42–3.12) | 1.16 (0.41–3.28) | 32/56 | 8.56 (1.08–67.8) | 8.52 (1.04–69.5) |
SELS | ||||||
RS34713741 | ||||||
CC | 57/132 | 1.0 | 1.0 | 46/132 | 1.0 | 1.0 |
CT | 87/151 | 1.32 (0.87–1.98) | 1.35 (0.87–2.07) | 75/151 | 1.42 (0.92–2.20) | 1.43 (0.91–2.27) |
TT | 10/31 | 0.77 (0.35–1.68) | 0.73 (0.32–1.68) | 20/31 | 1.87 (0.97–3.61) | 2.25 (1.13–4.48) |
P for trend | 0.772 | 0.79 | 0.037 | 0.017 | ||
SEPP1 | ||||||
RS7579 | ||||||
CC | 96/171 | 1.0 | 1.0 | 75/171 | 1.0 | 1.0 |
CT | 39/105 | 0.68 (0.43–1.06) | 0.65 (0.40–1.05) | 43/105 | 0.94 (0.60–1.47) | 0.99 (0.62–1.59) |
TT | 13/26 | 0.90 (0.44–1.83) | 1.01 (0.47–2.19) | 13/26 | 1.15 (0.56–2.36) | 1.35 (0.62–2.91) |
P for trend | 0.242 | 0.343 | 0.895 | 0.609 | ||
SEP15 | ||||||
RS5845 | ||||||
GG | 152/317 | 1.0 | 1.0 | 144/317 | 1.0 | 1.0 |
GA | 6/13 | 0.95 (0.35–2.56) | 0.94 (0.34–2.59) | 3/13 | 0.50 (0.14–1.79) | 0.49 (0.13–1.78) |
P | 0.921 | 0.913 | 0.286 | 0.278 | ||
SEP15 | ||||||
RS5859 | ||||||
CC | 152/315 | 1.0 | 1.0 | 142/315 | 1.0 | 1.0 |
CT | 6/13 | 0.94 (0.35–2.54) | 0.93 (0.34–2.57) | 3/13 | 0.50 (0.14–1.80) | 0.49 (0.14–1.79) |
P | 0.909 | 0.908 | 0.291 | 0.281 | ||
GPX4 | ||||||
RS713041 | ||||||
CC | 57/125 | 1.0 | 1.0 | 50/125 | 1.0 | 1.0 |
CT | 75/141 | 1.17 (0.76–1.78) | 1.22 (0.79–1.89) | 74/141 | 1.31 (0.85–2.02) | 1.28 (0.82–2.01) |
TT | 22/49 | 0.98 (0.54–1.78) | 1.02 (0.54–1.90) | 16/49 | 0.81 (0.42–2.56) | 0.79 (0.40–1.58) |
P for trend | 0.846 | 0.69 | 0.960 | 0.914 | ||
GPX1 | ||||||
RS1050450 | ||||||
CC | 130/254 | 1.0 | 1.0 | 111/254 | 1.0 | 1.0 |
CT + TT | 18/54 | 0.64 (0.36–1.15) | 0.65 (0.35–1.19) | 23/54 | 0.96 (0.56–1.65) | 1.09 (0.62–1.91) |