Table 2 Assessment of cell cycle analysis and apoptosis in HT-29 cell line treated with HT (a) and OL (b) for 72 h
HT-29 | Control (%) | 10 μM (%) | 25 μM (%) | 50 μM (%) | 100 μM (%) |
|---|---|---|---|---|---|
Hydroxytyrosol (a) | |||||
G1 | 62 | 63 | 60 | 57 | 47 |
S | 37 | 36 | 39.4 | 42 | 52 |
G2/M | 1 | 1 | 0.6 | 1 | 1 |
Apoptosis | 17.9 | 25.8 | 20.2 | 35.2 | 43* |
Oleuropein (b) | |||||
G1 | 60 | 49.5 | 60 | 58 | 59 |
S | 37 | 50 | 39 | 41 | 40 |
G2/M | 1 | 0.5 | 1 | 1 | 1 |
Apoptosis | 14.5 | 20.5 | 30 | 29.8 | 37.3* |