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Table 1 Physical characteristics and body fat distribution of normal-weight and obese women according to TNFA -308 G/A genotype

From: The -308 G/A polymorphism of the tumour necrosis factor-α gene modifies the association between saturated fat intake and serum total cholesterol levels in white South African women

 

Normal-weight, n = 88

Obese, n = 60

P-valuesa

GG

GA + AA

GG

GA + AA

BMI group

Genotype

Interaction

n

48

40

35

25

   

Age, years

29.8 ± 7.5

29 ± 7.1

33.4 ± 8.7

36.1 ± 7.8

0.034

0.652

0.191

Height, cm

1.67 ± 0.07

1.68 ± 0.07

1.67 ± 0.06

1.66 ± 0.07

0.739

0.403

0.458

Weight, kg

61.5 ± 7.0

62.2 ± 5.8

94.8 ± 12.3

101.3 ± 16.4

<0.001

0.732

0.130

BMI, kg/m2

21.6 ± 1.8

21.6 ± 1.9

33.9 ± 3.8

36.4 ± 4.6

<0.001

0.931

0.020

Body fat, %

27.7 ± 5.1

27.5 ± 5.3

46.2 ± 3.2

44.6 ± 4.3

<0.001

0.897

0.346

Waist, cm

77.6 ± 6.4

77.2 ± 6.0

106.1 ± 10.6

108.6 ± 11.1

<0.001

0.858

0.355

WHR

0.79 ± 0.05

0.78 ± 0.05

0.86 ± 0.07

0.85 ± 0.05

<0.001

0.569

0.855

VAT, cm2

64.1 ± 23.7

61.5 ± 17.9

152.7 ± 67.6

161.7 ± 55.9

<0.001

0.826

0.960

SAT, cm2

163 ± 67

169 ± 63

567 ± 140

516 ± 104

<0.001

0.833

0.131

  1. Values are mean ± standard deviation
  2. WHR waist-to-hip ratio, VAT visceral adipose tissue, SAT subcutaneous adipose tissue
  3. aP-values are from a linear model testing the interaction between BMI group and TNFA -308 G/A genotype, adjusted for age
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Genes & Nutrition

ISSN: 1865-3499

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