Table 5 All gene sets affected as a response to the oat bran meal compared with the control meal (P < 0.01, FDR q < 0.01) analysed with GSEA
Gene sets | FDR q-value | Gene set size |
|---|---|---|
Down-regulated | ||
REACTOME_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT | 0.0008 | 82 |
REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS | 0.0004 | 73 |
KEGG_RIBOSOME | 0.0003 | 75 |
REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | 0.0002 | 83 |
REACTOME_PEPTIDE_CHAIN_ELONGATION | 0.0002 | 74 |
REACTOME_VIRAL_MRNA_TRANSLATION | 0.0001 | 73 |
REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | 0.0001 | 78 |
REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | 0.0003 | 88 |
REACTOME_TRANSLATION | 0.0004 | 95 |
REACTOME_INFLUENZA_LIFE_CYCLE | 0.0028 | 120 |
REACTOME_INSULIN_SYNTHESIS_AND_SECRETION | 0.0043 | 110 |
WINNEPENNINCKX_MELANOMA_METASTASIS_UP | 0.0050 | 128 |
HUTTMANN_B_CLL_POOR_SURVIVAL_DN | 0.0050 | 51 |
PUJANA_BRCA2_PCC_NETWORK | 0.0061 | 368 |
PUJANA_XPRSS_INT_NETWORK | 0.0084 | 151 |
Up-regulated | ||
VERHAAK_AML_WITH_NPM1_MUTATED_UP | <0.0001 | 159 |
HUTTMANN_B_CLL_POOR_SURVIVAL_UP | <0.0001 | 243 |
RAGHAVACHARI_PLATELET_SPECIFIC_GENES | <0.0001 | 62 |
HSIAO_HOUSEKEEPING_GENES | <0.0001 | 346 |
MULLIGHAN_MLL_SIGNATURE_2_UP | <0.0001 | 361 |
RICKMAN_METASTASIS_DN | <0.0001 | 219 |
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN | 0.0002 | 272 |
REACTOME_RNA_POLYMERASE_I_PROMOTER_OPENING | 0.0001 | 28 |
JAATINEN_HEMATOPOIETIC_STEM_CELL_DN | 0.0001 | 193 |
MULLIGHAN_MLL_SIGNATURE_1_UP | 0.0001 | 330 |
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP | 0.0005 | 306 |
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP | 0.0016 | 347 |
ROSS_AML_WITH_AML1_ETO_FUSION | 0.0025 | 65 |
SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP | 0.0025 | 141 |
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN | 0.0023 | 167 |
HOSHIDA_LIVER_CANCER_SUBCLASS_S1 | 0.0023 | 212 |
JAATINEN_HEMATOPOIETIC_STEM_CELL_UP | 0.0025 | 257 |
RODWELL_AGING_KIDNEY_UP | 0.0025 | 284 |
HELLER_HDAC_TARGETS_UP | 0.0036 | 245 |
JISON_SICKLE_CELL_DISEASE_UP | 0.0035 | 161 |
RUTELLA_RESPONSE_TO_HGF_DN | 0.0037 | 206 |
OSMAN_BLADDER_CANCER_UP | 0.0044 | 330 |
MCLACHLAN_DENTAL_CARIES_UP | 0.0054 | 187 |
YANAGIHARA_ESX1_TARGETS | 0.0068 | 19 |
DELYS_THYROID_CANCER_UP | 0.0067 | 354 |
REN_ALVEOLAR_RHABDOMYOSARCOMA_DN | 0.0067 | 381 |
THUM_SYSTOLIC_HEART_FAILURE_UP | 0.0075 | 345 |
WIELAND_UP_BY_HBV_INFECTION | 0.0077 | 91 |