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Table 3 Expression of CYP3A1 mRNA in all studied age-groups with statistical analysis

From: Age-related changes in the mRNA levels of CYP1A1, CYP2B1/2 and CYP3A1 isoforms in rat small intestine

Age-group

Control

Induced with dexamethasone

2 Weeks

0.02 ± 0.02

0.016 ± 0.003

2 Months

0.007 ± 0.007

0.043 ± 0.03

4 Months

0.015 ± 0.009

0.06 ± 0.04

20 Months

0.003 ± 0.001

0.06 ± 0.01

28 Months

0.014 ± 0.001

0.25 ± 0.13

Comparison between age-groups (P-value)

2 Weeks versus 2 months

ns

ns

2 Weeks versus 4 months

ns

ns

2 Weeks versus 20 months

ns

P < 0.05

2 Weeks versus 28 months

ns

P < 0.01

2 Months versus 4 months

ns

ns

2 Months versus 20 months

ns

ns

2 Months versus 28 months

ns

P < 0.05

4 Months versus 20 months

ns

ns

4 Months versus 28 months

ns

P < 0.05

20 Months versus 28 months

P < 0.05

P < 0.05

  1. The data shown as integrated optical density (mean ± SD)
  2. ns Statistically not significant