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Fig. 7 | Genes & Nutrition

Fig. 7

From: Zinc deficiency or excess within the physiological range increases genome instability and cytotoxicity, respectively, in human oral keratinocyte cells

Fig. 7

The effects of zinc concentration in HOK cells on levels of a Poly (ADP-ribose) polymerase (PARP); b 8-oxoguanine glycosylase (OGG1); c p53; d γ-H2AX; (e) Caspase 3; f Metallothionein (MT) expressed in HOK cells following 9 days of culture, as determined by western blot analysis. S zinc sulphate, C zinc carnosine, 0: Zinc depleted cells, 0.4: 0.4 μM ZnS and C, 4: 4 μM ZnS and C, 16: 16 μM ZnS and C, 32: 32 μM ZnS and C, *intact PARP segments; **cleaved PARP segments. Representative western blot are shown in the inserts. Relative densitometric values are values for each sample divided by β-actin. Groups not sharing the same letter are significantly different to each other. (P values refer to One-way ANOVA analysis: P < 0.05). Results shown are mean ± standard error (n = 6)

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Genes & Nutrition

ISSN: 1865-3499

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