Fig. 2

a Averaging design, where urine spectra from approximately 5 subjects comprise each average. b For the classification of HGI/LGI diet groups, 80 samples from baseline were excluded from the model since no randomisation had taken place at this point. The 104 female and the 80 male spectra from visit 1, 3 and 6 month were averaged into the four diets groups LGI/LP, LGI/HP, HGI/LP and HGI/HP (without control) for each gender yielding 24 averaged spectra. c In the search for biomarkers associated with dietary fibre intake, 116 female and 84 male urine NMR spectra from baseline, month 1 and 6 were further averaged into HGI and LGI diets for each gender at each of the three time points yielding a total of 12 averaged spectra. Samples from month 3 were not included in the analysis, as no 3-day WFR were obtained at this time point