The association of lipoprotein lipase PvuII polymorphism and niacin intake in the prevalence of metabolic syndrome: a KMSRI-Seoul study

Table 3 Odds ratio (95% CI) for the risk of MetSyn according to levels of LPL mass with LPL gene polymorphism

LPL PvuII genotype	LPL mass (ng/mL) Tertile range		Non-MetSyn N (%)^a	MetSyn N (%)^a	OR (95% CI)^b	OR (95% CI)^c
P1P1/P1P2	Tertile 1^d	≦34.20	21 (11.7%)	48 (25.4%)	1.00^e	1.00^e
	Tertile 2	34.21–49.50	30 (16.7%)	39 (20.6%)	0.73 (0.43–1.25)	0.85 (0.36–1.98)
	Tertile 3	≧49.51	44 (24.4%)	24 (12.7%)	0.35 (0.20–0.62)	1.04 (0.49–2.21)
P2P2	Tertile 1	≦34.20	35 (19.4%)	47 (24.9%)	0.57 (0.34–0.96)	0.70 (0.34–1.47)
	Tertile 2	34.21–49.50	29 (16.1%)	20 (10.6%)	0.46 (0.25–0.83)	0.67 (0.28–1.63)
	Tertile 3	≧49.51	21 (11.7%)	11 (5.8%)	0.39 (0.19–0.78)	1.15 (0.42–3.13)
P for trend					0.002	0.588
Total subject	Tertile 1	≦34.20	56 (31.1%)	95 (50.3%)	1.00^e	1.00^e
	Tertile 2	34.21–49.50	59 (32.8%)	59 (31.2%)	0.82 (0.55–1.21)	0.89 (0.48–1.67)
	Tertile 3	≧49.51	65 (36.1%)	35 (18.5%)	0.49 (0.32–0.76)	1.26 (0.69–2.32)
P for trend					0.002	0.489

^aExcluding 90 subjects for control and 89 subjects for MetSyn with missing or unreliable data
^bORs and 95% CI calculated by unconditional logistic regression, adjusted for sex (men, women), age (<50, ≧50), BMI (<25, ≧25), physical activity (yes, no), smoking habits (smoker, ex-smoker, non-smoker), alcohol consumption (drinker, ex-drinker, non-drinker)
^cORs and 95% CI calculated by unconditional logistic regression, adjusted for sex (men, women), age (<50, ≧50), BMI (<25, ≧25), energy-adjusted niacin (continue), regular physical activity (yes, no), smoking habits (smoker, ex-smoker, non-smoker), alcohol consumption(drinker, ex-drinker, non-drinker)
^dEach cutoff point of tertile was based on the distribution of total subject
^eReference category

ISSN: 1865-3499