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Table 4 Odds ratio (95% CI) for MetSyn according to levels of dietary niacin intake with LPL gene polymorphism

From: The association of lipoprotein lipase PvuII polymorphism and niacin intake in the prevalence of metabolic syndrome: a KMSRI-Seoul study

LPL PvuII genotype

Niacin (mg/day)

Tertile range

Non-MetSyn

N (%)a

MetSyn

N (%)a

OR (95% CI)b

OR (95% CI)c

P1P1/P1P2

Tertile 1d

≦14.82

26 (20.5%)

24 (17.1%)

1.00e

1.00e

 

Tertile 2

14.83–17.80

21 (16.5%)

28 (20.0%)

1.08 (0.58–2.04)

1.26 (0.65–2.47)

 

Tertile 3

≧17.81

21 (16.5%)

29 (20.7%)

1.07 (0.57–2.02)

0.71 (0.36–1.41)

P2P2

Tertile 1

≦14.82

17 (13.4%)

30 (21.4%)

2.39 (1.25–4.56)

2.24 (1.16–4.35)

 

Tertile 2

14.83–17.80

23 (18.1%)

9 (6.4%)

0.34 (0.16–0.72)

0.26 (0.12–0.57)

 

Tertile 3

≧17.81

19 (15.0%)

20 (15.0%)

0.71 (0.36–1.40)

0.71 (0.46–1.10)

P for trend

    

0.149

0.038

Total subject

Tertile 1

≦14.82

43 (33.9%)

54 (38.6%)

1.00e

1.00e

 

Tertile 2

14.83–17.80

44 (34.6%)

37 (26.4%)

0.47 (0.29–0.76)

0.47 (0.28–0.78)

 

Tertile 3

≧17.81

40 (31.5%)

49 (35.0%)

0.61 (0.38–0.98)

0.46 (0.28–0.77)

P for trend

    

0.044

0.003

  1. aExcluding 143 subjects for control and 138 subjects for MetSyn with missing or unreliable data
  2. bORs and 95% CI calculated by unconditional logistic regression, adjusted for sex (men, women), age (<50, ≧50), and BMI (<25, ≧25)
  3. cORs and 95% CI calculated by unconditional logistic regression, adjusted for sex (men, women), age (<50, ≧50), BMI (<25, ≧25), physical activity (yes, no), smoking habits (smoker, ex-smoker, non-smoker), and alcohol consumption (drinker, ex-drinker, non-drinker)
  4. dEach cutoff point of tertile was based on the distribution of total subject
  5. eReference category