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Table 3 The genes selected by CovProc, LASSO, ELASTIC NET and GA methods for TIMP-1

From: Evaluation of multiple variate selection methods from a biological perspective: a nutrigenomics case study

CovProc

LASSO

ELASTIC NET

GA

Gene

f

r

Gene

f

r

Gene

f

r

Gene

f

r

Serpina3n

10

0.862

Serpina3n

10

0.862

Serpina3n

9

0.862

Serpina3n

7

0.862

Lcn2

10

0.839

Apcs

8

0.807

Apcs

7

0.807

Antxr2

0

0.581

Serpina10

10

0.839

Cobl

8

0.781

Cpb2

7

0.784

Keg1

0

−0.524

Saa2

10

0.828

B3galt1

8

0.780

Cobl

7

0.781

Cul1

0

0.462

Fgl1

10

0.827

Cpb2

6

0.784

B3galt1

6

0.780

Pscdbp

0

0.414

Itih4

10

0.821

Hapln4

5

0.709

Hapln4

3

0.709

Ugcgl1

0

0.401

Lbp

10

0.820

Cyb561

3

0.819

Spp1

3

0.631

LOC634731

0

0.395

Cyb561

10

0.819

Cxcl1

3

0.686

Arl6ip5

3

0.629

Ica1

0

0.367

Cpne8

10

0.813

Gm527

3

0.653

Cxcl1

2

0.686

Pilra

1

0.364

Apcs

10

0.807

2200001I15Rik

3

0.640

Gm527

2

0.653

Nudt18

0

0.338

Tnfrsf1a

10

0.805

Spp1

3

0.631

2200001I15Rik

2

0.640

Unk

1

0.329

Slc41a2

9

0.813

Arl6ip5

3

0.629

Serpina10

1

0.839

Cyp17a1

0

0.299

Itih3

9

0.790

Fgl1

2

0.827

Cyb561

1

0.819

Pdia6

0

0.296

Tmem176a

9

0.785

Acp6

2

−0.554

Tnfrsf1a

1

0.805

Rap2b

0

0.248

Stat3

9

0.784

Serpina10

1

0.839

Tmem176a

1

0.785

Pqlc2

0

0.236

Cpb2

9

0.784

Itih4

1

0.821

Mt2

1

0.784

Tlr8

0

0.196

Mt2

9

0.784

Tnfrsf1a

1

0.805

Abhd14b

1

−0.693

Tbc1d13

0

−0.176

Lrg1

9

0.783

Tmem176a

1

0.785

Polg2

1

−0.630

Cxxc5

0

−0.145

Cobl

9

0.781

Litaf

1

0.760

Edg5

1

0.585

1700006J14Rik

0

−0.145

B3galt1

9

0.780

Abhd14b

1

−0.693

Acp6

1

−0.554

NA

0

0.132

Ifitm2

9

0.776

Polg2

1

−0.630

Lcn2

0

0.839

Itfg1

0

0.131

Orm2

8

0.790

Edg5

1

0.585

Saa2

0

0.828

Fstl1

0

0.098

Zbp1

8

0.766

Lcn2

0

0.839

Fgl1

0

0.827

AI854517

0

0.081

Orm1

8

0.763

Saa2

0

0.828

Itih4

0

0.821

Ccdc79

0

−0.036

Litaf

8

0.760

Lbp

0

0.820

Lbp

0

0.820

5730410I19Rik

0

−0.029

Hp

7

0.765

Cpne8

0

0.813

Cpne8

0

0.813

Dync2li1

1

0.015

21

148

 

9

22

 

9

20

 

26

245

 
  1. f Number of occurrences in double cross-validation, r correlation coefficient of gene with TIMP-1 data. Genes present in the final single cross-validation model are in bold. The last row gives the number of genes in the final SCV model (bold) and the number selected at least once during DCV