Skip to main content
Fig. 6 | Genes & Nutrition

Fig. 6

From: Lactobacillus paracasei and Lactobacillus plantarum strains downregulate proinflammatory genes in an ex vivo system of cultured human colonic mucosa

Fig. 6

Ingenuity protein–protein interaction networks. The top-scoring network of genes induced in Inflamed compared to Control includes 21 focus molecules and has an assigned score of 39. This network correlates with the following functions: cell-to-cell signaling and interaction, inflammatory response, hematological system development and function (a). The top-scoring network of genes induced in iLP compared to Inflamed includes 18 focus molecules and has an assigned score of 31. This network correlates with the following functions: cell-to-cell interaction and signaling, hematological system development and function, immune cell trafficking (b). The top-scoring network of genes induced in iLP(A−) compared to Inflamed includes 22 focus molecules and has an assigned score of 41. This network correlates with the following functions: cellular development, cellular growth and proliferation, and inflammatory response (c). The top-scoring network of genes induced in iBL23 compared to Inflamed includes 18 focus molecules and has an assigned score of 32. This network correlates with the following functions: cell-to-cell signaling and interaction, inflammatory response, hematological system development and function (d). The intensity of the node color indicates the degree of up-(red) or down-(green) regulation. See Online Resource 8 for network legend

Back to article page