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Fig. 1 | Genes & Nutrition

Fig. 1

From: PTGS1, PTGS2, ALOX5, ALOX12, ALOX15, and FLAP SNPs: interaction with fatty acids in colon cancer and rectal cancer

Fig. 1

Inflammation risk score based on NSAID/aspirin use (score of 0 for recent user and score of 2 for non-recent user), smoking (score of 0 for non-recent smoker and 2 for recent smoker), BMI [score of 0 for normal (<25), 1 for overweight (25–29), and 2 for obese (>29)], total fat intake (score of 0 for lowest tertile, 1 for middle tertile, and 2 for highest tertile), arachidonic acid intake (score of 0 for highest tertile, 1 for middle tertile, and 2 for lowest tertile), and eicosapentaenoic acid intake (similar interactions assessed for SNP (rs20417) or group of SNPs (rs2066826, ra4648276 and 4648308) in high linkage disequilibrium (r 2 > 0. 8) with rs20432), adjusted for age, center, race, sex, and kcal. Shown are the significant results for a colon and b rectal cancer

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