Association of the C825T polymorphism in the GNB3 gene with obesity and metabolic phenotypes in a Taiwanese population

Table 1 Demographic and clinical characteristics of study subjects

Characteristic	Normal BMI < 24	Overweight 24 ≦ BMI < 27	Obesity BMI ≧ 27	P value^a	P value^b
No. of subjects	505	291	176
Age (years)	39.7 ± 12.3	40.9 ± 10.9	39.7 ± 10.9	0.126	0.960
Gender (male %)	50.9 %	70.1 %	73.3 %	<0.001	<0.001
BMI (kg/m²)	21.5 ± 1.8	25.3 ± 0.9	30.1 ± 3.2	<0.001	<0.001
Triglyceride (mg/dl)	95.6 ± 61.4	131.8 ± 86.1	153.3 ± 106.7	<0.001	<0.001
Waist (cm)	74.9 ± 7.4	84.6 ± 5.9	94.4 ± 8.9	<0.001	<0.001
Systolic blood pressure (mmHg)	122.1 ± 14.3	128.5 ± 12.6	135.2 ± 17.6	<0.001	<0.001
Diastolic blood pressure (mmHg)	78.2 ± 9.9	83.2 ± 10.2	87.4 ± 12.5	<0.001	<0.001
Fasting glucose (mg/dl)	86.6 ± 21.3	89.4 ± 22.8	91.8 ± 25.5	0.081	0.009
Total cholesterol (mg/dl)	186.7 ± 34.9	192.6 ± 32.2	190.1 ± 33.1	0.017	0.264

Data are presented as mean ± standard deviation
BMI body mass index
^a P values are obtained by comparing the normal subjects with overweight subjects
^b P values are obtained by comparing the normal subjects with obesity subjects

ISSN: 1865-3499