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Table 1 Lactase activity in relation to G/A -22018 variant among Indian children

From: Correlation of G/A -22018 single-nucleotide polymorphism with lactase activity and its usefulness in improving the diagnosis of adult-type hypolactasia among North Indian children

 

Genotype

Total

N = 231

P value

G/G -22018

n = 129

G/A + A/A -22018

n = 102

(G/A = 91, A/A = 11)

Lactase

14.5 ± 9.8 (3–46)*

29.1 ± 7.5 (8–54)

21 ± 11.4 (3–54)

<0.001†

L/S ratio‡

0.15 ± 0.11 (0.04–0.54)

0.31 ± 0.11 (0.07–0.67)

0.22 ± 0.14 (0.04–0.67)

<0.001†

  1. * Lactase activity is expressed as U/g protein, mean ± SD (range) for all such values
  2. † P value based on nonparametric Mann–Whitney test
  3. ‡ L/S lactase/sucrase ratio
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Genes & Nutrition

ISSN: 1865-3499

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