Skip to main content

Table 1 Characteristics of study participants

From: The maternal folate hydrolase gene polymorphism is associated with neural tube defects in a high-risk Chinese population

Characteristic

Case (148a)

n (%)b

Control (299a)

n (%)b

p c

Age (year)

144

298

0.096

 <20

9 (6.25)

22 (7.38)

 20–29

112 (77.78)

203 (68.12)

 >29

23 (15.97)

73 (24.50)

Educational level

138

269

 

 <Middle school graduation

14 (10.14)

25 (9.29)

0.157

 Middle school graduation

106 (76.81)

188 (69.89)

 >Middle school graduation

18 (13.04)

56 (20.81)

Gravidity (n)

137

269

 

 1

9 (6.57)

27 (10.04)

0.507

 2

15 (10.95)

29 (10.78)

 ≥3

113 (82.48)

213 (79.18)

Parity (n)

137

269

 

 0

14 (10.22)

27 (10.04)

0.530

 1

10 (7.30)

29 (10.78)

 ≥2

113 (82.48)

213 (79.18)

Periconceptional folic acid used

123

254

 

 No

116 (94.31)

246 (96.85)

0.265

 Yes

7 (5.69)

8 (3.15)

Gestational week

145

291

 

 <21

82 (56.55)

203 (69.76)

0.016

 21–29

41 (28.28)

63 (21.65)

 ≥30

22 (15.17)

25 (8.59)

  1. aReferes to the number of subject
  2. bPercentages may not equal 100 because of rounding
  3. cChi-square test was used to calculate the p values
  4. dThe “periconceptional” refers to the month before conception and the first 3 months after conception