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Table 2 Hepatic proteome of the male offspring at 12 months of age

From: A methyl-deficient diet fed to rats during the pre- and peri-conception periods of development modifies the hepatic proteome in the adult offspring

Spot ID no

ID

NCBI

CON

MD

P

Mean

SEM

Mean

SEM

Energy metabolism

8302

L-lactate dehydrogenase (EC 1.1.1.27) chain M

P04642

426.3

52.5

264.4

28.7

0.022

2009

Cytidylate kinase

Q4KM73

58.2

5.0

43.9

3.5

0.049

6606

UDP-glucose pyrophosphorylase 2.

Q4V8I9

158.6

18.9

104.2

13.8

0.045

4207

Electron transfer flavoprotein subunit beta (beta-ETF)

Q68FU3

145.2

5.7

178.8

13.5

0.026

Antioxidant defence

7604

Catalase (EC 1.11.1.6).

P04762

142.6

9.4

85.4

17.9

0.009

4213

HAGH (Hydroxyacylglutathione hydrolase) protein

O35952

10.8

2.6

20.9

3.1

0.023

3606

Selenium binding protein 2.

Q8VIF7

235.9

23.1

341.8

41.6

0.031

3801

5-oxoprolinase (ATP-hydrolysing) (EC 3.5.2.9)

P97608

9.4

1.6

5.2

0.8

0.046

Amino acid and peptide metabolism

5307

Ornithine carbamoyltransferase (EC 2.1.3.3) precursor

P00481

102.2

8.5

69.5

3.5

0.006

2811

Acylaminoacyl peptidase (EC 3.4.19.1)

P13676

8.8

1.9

16.9

3.0

0.033

6402

Aspartate transaminase (EC 2.6.1.1), cytosolic

P13221

288.6

26.7

209.5

18.5

0.038

Miscellaneous

2515

Aldehyde dehydrogenase 9 family, member A1

Q9JLJ3

318.0

29.6

502.1

63.7

0.012

3808

Mannosidase, alpha, class 2C, member 1.

Q5M9I2

4.3

0.7

7.6

1.0

0.015

5305

3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)

P31210

56.4

10.3

125.6

27.1

0.020

4303

3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)

P31210

408.9

54.8

604.9

54.5

0.026

  1. Offspring were from dams fed complete (CON) or methyl-deficient (MD) diets. Data are mean pixel density ± SEM, n = 9 for CON and n = 7 for MD. Data compared by Student’s t test