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Table 3 Gene expression in the liver of male offspring at 6 months of age

From: A methyl-deficient diet fed to rats during the pre- and peri-conception periods of development modifies the hepatic proteome in the adult offspring

Gene

n

CON

MD

P

Mean

SEM

Mean

SEM

PEPCK(T)

16

3.39

0.31

4.07

0.35

0.157

GAPDH(T)

16

2.80

0.10

3.03

0.13

0.162

UGDH(T)

8

5.69

0.14

6.03

0.28

0.298

PPAR-alpha

8

5.39

0.26

5.90

0.45

0.340

PPAR-gamma

16

6.06

0.61

6.36

0.47

0.704

SREBP-1c

16

1.48

0.13

1.61

0.12

0.461

GccR

16

3.69

0.13

3.76

0.17

0.719

ACC-1

8

5.88

0.40

6.06

0.07

0.817

L-CPT

16

2.53

0.15

2.68

0.17

0.521

  1. Offspring were from dams fed complete (CON) or methyl-deficient (MD) diets. All data are expressed in arbitrary units as relative expression corrected for 18S rRNA. n = number of animals, 1 per litter chosen at random from the total pool of 18 litters (CON) and 17 litters (MD). Data compared by Student’s t test
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Genes & Nutrition

ISSN: 1865-3499

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