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Table 5 Standard least-squares regression analysis to examine whether transsulphuration pathway–related variables predict recumbent diastolic and systolic blood pressure (mm Hg). Data are examined without reference to the standard >140/90 mm Hg index for defining hypertension. Data show p (r 2 and slope estimate) values for all subjects, males and females

From: Hydrogen sulphide-related thiol metabolism and nutrigenetics in relation to hypertension in an elderly population

Variable

All subjects

Males

Females

Diastolic

Systolic

Diastolic

Systolic

Diastolic

Systolic

Homocysteine

NS

NS

NS

NS

NS

NS

Cysteine

<0.0001 (r 2 = 0.082, −0.0719)

0.0407 (r 2 = 0.018, −0.0523)

0.0409 (r 2 = 0.046, −0.0568)

NS

<0.0001 (r 2 = 0.113, −0.0819)

0.0463 (r 2 = 0.029, −0.0640)

Glutathione

NS

NS

NS

NS

NS

NS

Dietary natural folate

0.0513 (r 2 = 0.0167, 0.0102)

NS

0.0024 (r 2 = 0.0990, 0.0237)

0.0256 (r 2 = 0.0548, 0.0267)

NS

NS

Dietary synthetic folate

NS

NS

NS

NS

NS

NS

Dietary vitamin B12

NS

NS

NS

NS

NS

NS

Dietary vitamin B6

0.0860 (r 2 = 0.0130, 0.5603)

NS

0.0052 (r 2 = 0.0846, 1.3547)

0.0722 (r 2 = 0.0359, 1.3398)

NS

0.0178 (r 2 = 0.0409, −1.6171)

CTH-G1364T

NS

NS

0.0217 (r 2 = 0.083)

NS

NS

NS

CBS-844ins68

NS

NS

NS

NS

NS

NS