Fig. 4
Effect of 24-h pretreatment with AS or FS on HO-1 and NQO-1 gene expression in HUVECs exposed for 24 h to 32 % O2 (mild hyperoxic conditions) or to 21 % O2 (normoxic conditions). Cells treated with FS and exposed to normoxic conditions were used as negative control. Values are expressed as 2−ΔΔCt normalized to FS-treated cells exposed to normoxic conditions. *P < 0.05 versus FS-treated cells exposed to normoxic conditions. °P < 0.05 versus FS-treated cells exposed to mild hyperoxic conditions. § P < 0.05 versus AS-treated cells exposed to normoxic conditions. a HO-1, heme oxygenase-1; b NQO-1, NAD(P)H:quinone oxidoreductase 1. AS, human serum obtained after Medox® capsules consumption; FS, human serum obtained immediately before Medox® capsules consumption