Beneficial effects of flaxseed oil and fish oil diet are through modulation of different hepatic genes involved in lipid metabolism in streptozotocin–nicotinamide induced diabetic rats

Table 3 Effect of flaxseed oil or fish oil diets on plasma fatty acid profile of STZ-NIC-induced diabetic rats

Fatty acids (g/100 g fatty acids)	C	DC	DFL	DF	CFL	CF
Linoleic acid	02.56 ± 00.44	01.89 ± 00.41	02.81 ± 00.39	02.45 ± 00.40	02.24 ± 00.34	02.23 ± 00.51
ALA	03.40 ± 00.45	–	07.53 ± 01.34	–	01.11 ± 00.33	–
ARA	04.81 ± 00.53	01.16 ± 00.28^###	02.83 ± 00.27	01.80 ± 00.41	03.25 ± 00.57	03.12 ± 00.69
EPA	08.01 ± 00.84	05.25 ± 00.16^#	08.41 ± 00.53*	08.39 ± 00.58*	08.42 ± 00.80	08.25 ± 00.92
DHA	10.05 ± 01.01	04.33 ± 00.67^###	11.53 ± 00.84***	10.50 ± 01.09***	11.43 ± 00.99	11.50 ± 01.03
Omega-3	21.46 ± 01.24	09.58 ± 00.63^###	27.48 ± 01.01***	18.89 ± 01.50***	20.96 ± 01.40	19.75 ± 01.69
Omega-6	07.37 ± 00.74	03.06 ± 00.67^###	05.65 ± 00.21*	04.25 ± 00.68	05.49 ± 00.34	05.35 ± 00.67
n − 3: n − 6	03.06 ± 00.33	03.69 ± 00.68	04.91 ± 00.30	05.39 ± 01.51	03.99 ± 00.56	03.94 ± 00.43

All values are expressed as mean ± SEM (n = 6). Comparisons were done between the control group and each individual group by Dunnet’s multiple comparison test. (^# P < 0.05, ^### P < 0.001, when compared against control group, * P < 0.05, *** P < 0.001, when compared against diabetic control group)
C Control, DC diabetes control, DFL diabetes + flaxseed oil, DF diabetes + fish oil, CFL control + flaxseed oil, CF control + fish oil

ISSN: 1865-3499