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Table 1 Biochemical parameters of responders and non-responders pre- and post-n-3 PUFA supplementation

From: Differences in metabolomic and transcriptomic profiles between responders and non-responders to an n-3 polyunsaturated fatty acids (PUFAs) supplementation

 

Responders (n = 6)

Non-responders (n = 6)

P value between resp. and non-resp.

 

Pre-n-3 PUFAs

Post-n-3 PUFAs

P value

Pre-n-3 PUFAs

Post-n-3 PUFAs

P value

Pre-n-3 PUFAs

Delta (post- and pre-n-3 PUFAs)

Gender

2 men (33 %) and 4 women (67 %)

1 man (16 %) and 5 women (83 %)

  

Age (years)

40 ± 4 years

30 ± 4 years

NS

 

BMI (kg/m²)

29.9 ± 1.5

  

30.5 ± 2.7

  

NS

NS

Triacylglycerolsa (mmol/L)

1.75 ± 0.47

0.99 ± 0.23

0.0002

1.03 ± 0.15

1.12 ± 0.17

0.045

NS

0.0153

Cholesterol (mmol/L)

 Total

5.00 ± 0.28

5.03 ± 0.42

NS

5.02 ± 0.43

4.88 ± 0.33

NS

NS

NS

 LDL

2.76 ± 0.37

3.03 ± 0.42

NS

2.85 ± 0.43

2.57 ± 0.33

NS

NS

0.0443

 HDLa

1.43 ± 0.16

1.54 ± 0.18

0.0267

1.70 ± 0.11

1.80 ± 0.12

NS

NS

NS

Ratio TC/HDL-C

3.66 ± 0.37

3.39 ± 0.33

0.0001

3.05 ± 0.41

2.79 ± 0.30

0.0018

NS

NS

Apo-B100 (g/L)

0.87 ± 0.08

0.88 ± 0.08

NS

0.81 ± 0.12

0.80 ± 0.08

NS

NS

NS

Ratio LDL/Apo-B

3.18 ± 0.69

3.42 ± 0.64

0.0108

3.51 ± 0.48

3.18 ± 0.48

0.0247

NS

0.0039

Glucose (mmol/L)

5.33 ± 0.19

5.42 ± 0.17

NS

4.77 ± 0.21

4.98 ± 0.29

NS

0.0058

NS

Insulin (pmol/L)

68.80 ± 20.45

90.83 ± 27.54

NS

73.00 ± 8.83

89.17 ± 5.80

NS

NS

NS

CRPa(mg/L)

2.11 ± 0.95

2.13 ± 1.06

NS

1.20 ± 0.40

1.10 ± 0.40

NS

NS

NS

  1. Data are shown as mean ± SEM
  2. TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol
  3. a P value derived from transformed data