Table 6 Changes in the expression of genes in PBMCs involved in arachidonic acid metabolism after n-3 PUFA supplementation in responders and non-responders (P = 0.52 and P = 0.11, respectively)
Gene symbol | Gene name | Responders (n = 6) | Non-responders (n = 6) |
|---|---|---|---|
ALOX5 | Arachidonate 5-lipoxygenase |  | −1.229 |
ALOX15 | Arachidonate 15-lipoxygenase | 1.216 | Â |
ALOX15B | Arachidonate 15-lipoxygenase, type B | Â | 1.302 |
CYP2F1 | Cytochrome P450, family 2, subfamily F, polypeptide 1 |  | −1.214 |
CYP2J2 | Cytochrome P450, family 2, subfamily J, polypeptide 2 | Â | 1.235 |
CYP4F3 | Cytochrome P450, family 4, subfamily F, polypeptide 3 | −1.269 | −1.545 |
CYP4F8 | Cytochrome P450, family 4, subfamily F, polypeptide 8 |  | −1.326 |
GGT1 | Gamma-glutamyltransferase 1 | 1.203 | −1.313 |
GGT2 | Gamma-glutamyltransferase 2 | Â | 1.324 |
GGT3 | Gamma-glutamyltransferase 3 pseudogene | −1.298 |  |
GGT7 | Gamma-glutamyltransferase 7 | −1.307 | 1.274 |
GPX1 | Glutathione peroxidase 1 |  | −1.261 |
LCAT | Lecithin-cholesterol acyltransferase | Â | 1.225 |
PLA2G2A | Phospholipase A2, group IIA (platelets, synovial fluid) | −1.203 |  |
PLA2G2C | Phospholipase A2, group IIC | Â | 1.396 |
PLA2G2D | Phospholipase A2, group IID | Â | 1.232 |
PLA2G2F | Phospholipase A2, group IIF | 1.294 | Â |
PLA2G4A | Phospholipase A2, group IVA (cytosolic, calcium-dependent) |  | −1.250 |
PLA2G6 | Phospholipase A2, group VI (cytosolic, calcium-independent) | 1.378 | Â |