Table 1 Characteristics of the population (median with 25–75 percentiles)
Normal weight n = 11 | ARO n = 10 | MHO n = 9 | P a | P b | P c | |
|---|---|---|---|---|---|---|
Gender (m/f) | 4/7 | 9/1 | 5/4 | |||
Age (years) | 47 (42–54) | 52 (43–59) | 49 (42–63) | – | – | – |
Weight (kg) | 65.8 (63.1–79.1) | 102.7 (96.0–113.8) | 104.4 (93.3–110.6) | <0.001 | <0.001 | – |
BMI (kg/m2) | 23 (21–24) | 32 (30–34) | 33 (30–37) | <0.001 | <0.001 | – |
TAG (mmol/L) | 0.6 (0.4–0.9) | 2.3 (1.7–2.7) | 1.0 (0.8–1.3) | <0.001 | <0.001 | <0.001 |
Total cholesterol (mmol/L) | 4.7 (4.2–5.0) | 5.8 (5.4–6.1) | 5.1 (4.3–5.2) | <0.001 | – | 0.002 |
HDL (mmol/L) | 1.6 (1.4–2.2) | 1.1 (0.9–1.1) | 1.4 (1.2–1.5) | <0.001 | 0.032 | 0.001 |
LDL (mmol/L) | 2.3 (2.1–2.6) | 3.8 (3.4–3.9) | 2.9 (2.6–3.3) | <0.001 | 0.009 | 0.002 |
Glucose (mmol/L) | 5.1 (4.3–5.3) | 5.6 (4.1–6.3) | 5.4 (4.8–5.7) | 0.044 | – | – |
Insulin (pmol/L) | 40 (19–59) | 75 (60–107) | 65 (52–102) | 0.001 | 0.012 | 0.033 |
HOMA dir | 1.4 (0.6–2.0) | 3.0 (2.3–4.3) | 2.2 (1.7–3.7) | <0.001 | 0.015 | 0.009 |
HbA1c (%) | 5.1 (4.9–5.4) | 5.3 (5.0–5.9) | 5.6 (5.3–5.7) | – | 0.039 | – |
C-peptide (pmol/L) | 482 (279–584) | 942 (821–1171) | 889 (754–1155) | <0.001 | <0.001 | – |
hsCRP (mg/L) | 0.5 (0.3–1.1) | 1.6 (0.8–3.5) | 2.2 (0.8–2.7) | 0.020 | 0.033 | – |