The genetics of childhood obesity and interaction with dietary macronutrients

Genes & Nutrition

Table 1 A list of 35 obesity susceptibility genes, reference SNPs, susceptible subjects, and phenotypes identified using GWAS adapted from Meyre et al. (2009), den Hoed et al. (2010), Sandholt et al. (2010), Wu et al. (2010), and Zhao et al. (2011)

Chromosome	Nearest gene	Reference SNP	Subjects	Phenotypes
1	NEGR1	rs2815752	Adults	Weight, obesity, BMI
1	TNN13K	rs1514175	Adults, children	BMI
1	PTBP2	rs1555543	Adults	BMI
1	SEC16B	rs543874	Adults, children	BMI
2	TMEM18	rs2867125	Adults, children	Weight, obesity, BMI
2	RBJ	rs713586	Adults, children	BMI
2	FANCL	rs887912	Adults	BMI
2	LRP1B	rs2890652	Adults	BMI
3	CADM2	rs13078807	Adults	BMI
3	ETV5	rs9816226	Adults	Weight, obesity, BMI
4	GNPDA2	rs10938397	Adults, children	Weight, obesity, BMI
4	SLC39A8	rs13107325	Adults	BMI
5	FLJ35779	rs2112347	Adults, children	BMI
5	ZNF608	rs4836133	Adults	BMI
6	NUDT3	rs206936	Adults	BMI
6	TFAP2B	rs987237	Adults	BMI
9	LRRN6C	rs10968576	Adults, children	BMI
10	PTER	rs10508503	Adults, children	BMI
11	RPL27A	rs4929949	Adults	BMI
11	BDNF	rs10767664	Adults, children	Weight, obesity, BMI
11	MTCH2	rs3817334	Adults	BMI
12	FAIM2	rs7138803	Adults, children	Weight, obesity, BMI
13	MTIF3	rs4771122	Adults	BMI
14	PRKD1	rs11847697	Adults	BMI
14	NRXN3	rs10150332	Adults, children	BMI
15	MAP2K5	rs2241423	Adults	BMI
16	GPRC5B	rs12444979	Adults	BMI
16	SH2B1	rs7359397	Adults	Weight, obesity, BMI
16	MAF	rs1424233	Adults, children	BMI
16	FTO	rs1558902	Adults, children	Weight, obesity, BMI
18	MC4R	rs571312	Adults, children	Weight, obesity, BMI
18	NPC1	rs1805081	Adults, children	BMI
19	KCTD15	rs299941	Adults	BMI
19	QPCTL	rs2287019	Adults, children	BMI
19	TMEM160	rs3810291	Adults	BMI

ISSN: 1865-3499