Fig. 4

HMGCR gene (a) and protein (b) expression in the liver of WK and SH rats fed the different diets. Hmgcr gene expression (a). Data in the graph are represented as [(sample ratio) − (unitary calibrator group ratio)]; significant differences were evaluated with Taylor’s series statistical analysis. Gene expression in each group (n = 7) is reported as median, range (min–max), and 95 % CI in the corresponding table, where statistic pairs, p value and resulting differences are also indicated. HMGCR protein expression (b). Data in the graph are mean ± SD of four animals per group and are represented as densitometric value normalized on actin. Statistical analysis was performed by the one-way ANOVA using Tukey’s as post-test; different superscript letters indicate statistical significance (at least p < 0.05)