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Table 3 Baseline characteristics and weight loss of all completers according to the risk group

From: Genetic modulation of the serotonergic pathway: influence on weight reduction and weight maintenance

 

Female (n = 60)

Male (n = 30)

R+

R−

p

R+

R−

p

Fraction (n [%])

6 [10]

54 [90]

 

5 [16.7]

25 [83.3]

 

Age (years)

48 ± 10

44 ± 13

0.51*

50 ± 12

46 ± 12

0.49*

Nicotine use (n [%])

3 [50]

12 [22.2]

0.15†

0 [0]

2 [8]

0.51†

Systolic blood pressure (mmHg)

145.3 ± 17.1

139.1 ± 18.0

0.29*

157.2 ± 11.5

139.4 ± 17.5

0.03*

Diastolic blood pressure (mmHg)

85.2 ± 5.0

88.9 ± 12.3

0.47*

94.4 ± 10.4

86.9 ± 8.2

0.15*

Glucose (mg/dL)

106.0 ± 21.5

103.0 ± 20.8

0.76*

106.2 ± 10.1

113.8 ± 30.2

0.61*

Total cholesterol (mg/dL)

211.0 ± 44.3

204.4 ± 36.9

0.82*

222.4 ± 31.7

210.3 ± 45.2

0.47*

LDL cholesterol (mg/dL)

138.4 ± 34.8

126.9 ± 31.1

0.55*

124.8 ± 33.3

123.6 ± 33.9

0.94*

HDL cholesterol(mg/dL)

49.2 ± 7.8

52.5 ± 13.1

0.70*

43.0 ± 5.8

42.4 ± 7.2

0.62*

Triacylglycerols (mg/dL)

116.8 ± 51.9

124.3 ± 44.3

0.62*

233.5 ± 83.8

208.8 ± 118

0.39*

Weight (kg) T0

119.3 ± 17.8

119.2 ± 20.1

0.89*

127.3 ± 18.5

136.6 ± 27.8

0.62*

BMI (kg/m²) T0

44.0 ± 3.1

42.0 ± 6.5

0.27*

41.1 ± 7.2

42.9 ± 8.0

0.60*

Weight (kg) T2

106.7 ± 25.0

98.3 ± 18.5

0.43*

100.0 ± 11.7

108.4 ± 27.8

0.70*

BMI (kg/m²) T2

39.1 ± 6.2

34.7 ± 6.1

0.09*

32.3 ± 4.8

34.1 ± 8.4

0.93*

Weight (kg) T0–2

−12.6 ± 8.4

−20.9 ± 9.8

0.05*

−27.3 ± 10.9

−28.2 ± 15.7

0.93*

BMI (kg/m²) T0–2

−4.9 ± 3.5

−7.4 ± 3.4

0.09*

−8.8 ± 3.6

−8.8 ± 4.8

0.85*

Weight (kg) T0–1

−16.7 ± 4.6

−18.4 ± 4.7

0.61*

−24.2 ± 9.3

−23.4 ± 6.4

0.68*

BMI (kg/m²) T0–1

−6.3 ± 1.5

−6.5 ± 1.6

0.87*

−7.8 ± 3.0

−7.3 ± 1.8

0.66*

Weight (kg) T1–2

+4.4 ± 10.1

−2.5 ± 7.4

0.11*

−3.0 ± 7.2

−4.8 ± 11.5

0.91*

BMI (kg/m²) T1–2

+1.4 ± 3.6

−0.9 ± 2.6

0.14*

−1.1 ± 2.2

−1.5 ± 3.6

0.93*

  1. T0: start of the program, T1: after weight reduction phase, T2: after weight maintenance phase and end of the program
  2. * Mann–Whitney U test; † χ 2 test
  3. Mean values ± SD and p values are given. Significant p values (p ≤ 0.05) are standing out in bold
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Genes & Nutrition

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