Fig. 2
From: Cellular polarity in aging: role of redox regulation and nutrition
Molecular pathways of cellular polarity that are regulated by ROS, in different physiological processes altered during aging. AMPK has a central role in regulating several molecular pathways that are master players in the establishment of cellular polarity. ROS are responsible for adjusting cellular polarity to the oxidative status, through redox regulation of angiogenesis, tight junctions, transcription, and cytoskeleton