Genes & Nutrition

Table 2 Serum lipid content in rats fed diets containing either casein or increasing amounts of alcohol-washed SPI

From: Dietary supplementation with soy isoflavones or replacement with soy proteins prevents hepatic lipid droplet accumulation and alters expression of genes involved in lipid metabolism in rats

	mg/ml
	D1¹	D2¹	D3¹	D4¹	D5¹
Male
Cholesterol
Total	1.05 ± 0.10^a	0.95 ± 0.08^a	0.90 ± 0.09^ab	0.74 ± 0.06^b	0.94 ± 0.10^a
Free	0.23 ± 0.02^a	0.21 ± 0.02^ab	0.20 ± 0.02^ab	0.17 ± 0.01^b	0.24 ± 0.03^a
LDL²	0.78 ± 0.08^a	0.70 ± 0.06^ab	0.68 ± 0.07^ab	0.57 ± 0.04^b	0.69 ± 0.06^ab
HDL²	0.57 ± 0.05^a	0.51 ± 0.04^ab	0.49 ± 0.04^ab	0.43 ± 0.03^b	0.55 ± 0.05^a
Triglyceride	0.68 ± 0.11	0.85 ± 0.17	0.98 ± 0.22	0.67 ± 0.12	0.90 ± 0.16
FFA² (mmol/L)	0.61 ± 0.02	0.58 ± 0.03	0.59 ± 0.06	0.49 ± 0.04	0.54 ± 0.03
Female
Cholesterol
Total	0.92 ± 0.07	0.89 ± 0.07	0.93 ± 0.04	0.93 ± 0.10	0.91 ± 0.07
Free	0.24 ± 0.02	0.24 ± 0.02	0.25 ± 0.02	0.24 ± 0.03	0.23 ± 0.01
LDL	0.64 ± 0.05	0.61 ± 0.05	0.67 ± 0.04	0.71 ± 0.07	0.69 ± 0.05
HDL	0.53 ± 0.04	0.51 ± 0.03	0.50 ± 0.02	0.56 ± 0.06	0.54 ± 0.03
Triglyceride	0.58 ± 0.16	0.48 ± 0.10	0.42 ± 0.06	0.59 ± 0.09	0.41 ± 0.11
FFA (mmol/L)	0.73 ± 0.07^a	0.60 ± 0.04^b	0.66 ± 0.06^ab	0.62 ± 0.04^ab	0.61 ± 0.02^b

Values are means ± SEM, n = 8. Means in the same row with different superscripts differ, p < 0.05
¹D1: 20 % casein; D2: 20 % casein + 50 mg isoflavones/kg diet; D3: 15 % casein + 5 % SPI; D4: 10 % casein + 10 % SPI; D5: 20 % SPI
² LDL low density lipoprotein, HDL high density lipoprotein, FFA free fatty acids

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