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Table 3 Differentially expressed liver proteins in the female rats fed diets containing either 20 % casein or SPI

From: Dietary supplementation with soy isoflavones or replacement with soy proteins prevents hepatic lipid droplet accumulation and alters expression of genes involved in lipid metabolism in rats

Protein

Ratio ofSPI/Casein

p value

FA β-oxidation

 Peroxisomal acyl-coenzyme A oxidase 1

1.34

0.002

 Long-chain enoyl-CoA hydratase/3-hydroxycyl-CoA dehydrogenase α

1.42

0.002

 Peroxisomal multifunctional enzyme type 2

1.89

0.026

Lipolysis

 Liver carboxylesterase 3

1.49

0.037

 Carboxylesterase

1.86

0.058

 Acyl-CoA synthetase

2.11

0.070

 ATP synthase γ

1.56

0.015

FA synthesis

 Fatty acid synthase

−1.63

0.019

 Cytoplasmic aconitate hydratase

−1.87

0.094

 Glucose-6-phosphate dehydrogenase

−2.01

0.091

Glycolysis

 Glyceraldehyde 3-phosphate-dehydrogenase

1.84

0.003

 Cytochrome b-c1 complex subunit 2

1.33

0.034

 Fructose-biphosphatase

1.60

0.097

 Biliverdin reductase A precursor

−1.38

0.06

 Pyruvate dehydrogenase E1 α1

−1.36

0.00091

Cholesterol metabolism

 Non-specific lipid-transfer protein

2.45

0.0027

 SEC14-like protein 2

1.46

0.00027

Amino acid metabolism

 Sarcosine dehydrogenase

−2.62

0.0063

 Carbamoyl-phosphate synthase

−1.53

0.0180

 Ω-amidase NIT2

1.31

0.0072

 S-adenosylmethionine synthase isoform type-1

1.35

0.0017

 Cystathionine γ-lyase

1.77

0.0360

 Alanine–glyoxylate aminotransferase 2

2.04

0.0013

 Dihydrodipicolinate synthase-like

2.14

0.0055

 4-trimethylaminobutyraldehyde dehydrogenase

2.19

3.9E − 05

 Kynurenine aminotransferase III, isoform CRA_a

1.78

0.02

Oxidative stress

 Glutathione S-transferase Ω-1

1.37

0.046

 Glutathione S-transferase α-2

1.32

0.038

 Hydroxyacid oxidase 1

1.56

0.001

 Catalase

1.98

0.0002

Others

 Low M(r) phosphotyrosine protein phosphatase isoenzyme AcP1

1.32

0.012

 Rhodanese

1.90

0.0002

 Ubfd1 protein

1.35

0.022

 rCG50422, isoform CRA_a

−1.83

−0.051

 Cytokeratin 8 polypeptide

−1.67

0.011

 F alloantigen

−1.48

0.005

 Complement component C8 α

−1.43

0.015

 Early endosome antigen 1

−1.40

0.032

 Hypothetical protein LOC499136

−1.39

0.001

 PREDICTED: ribosomal protein L9-like

1.30

0.006

 Keratin, type I cytoskeletal 10

1.37

0.002

 Alcohol sulfotransferase

1.71

0.009

 PREDICTED: hypothetical protein

1.73

0.013

 rCG55900

1.73

0.001

 Uricase

1.83

0.0005