Table 2 Genotype frequencies of SEP15 and SLC30A3 polymorphisms according to the presence of memory deficits
Genotype | Overall n (%) | Type of memory | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Short-term verbal | Long-term verbal | Short-term visual | Long-term visual | Verbal learning memory | |||||||
Normal n (%) | Deficit n (%) | Normal n (%) | Deficit n (%) | Normal n (%) | Deficit n (%) | Normal n (%) | Deficit n (%) | Normal n (%) | Deficit n (%) | ||
SEP15 | |||||||||||
rs561104 | |||||||||||
CC | 33 (13.8) | 28 (14.5) | 5 (10.6) | 32 (14.8) | 1 (4.2) | 29 (15.7) | 4 (7.3) | 26 (14.7) | 7 (11.1) | 24 (12.6) | 9 (18.0) |
CT | 118 (49.2) | 90 (46.6) | 28 (59.6) | 105 (48.6) | 13 (54.2) | 87 (47.0) | 31 (56.4) | 86 (48.6) | 32 (50.8) | 94 (49.5) | 24 (48.0) |
TT | 89 (37.1) | 75 (38.9) | 14 (29.8) | 79 (36.6) | 10 (41.7) | 69 (37.3) | 20 (36.4) | 65 (36.7) | 24 (38.1) | 72 (37.9) | 17 (34.0) |
p | 0.281 | 0.356 | 0.230 | 0.778 | 0.604 | ||||||
rs5859 | |||||||||||
GG | 138 (57.5) | 110 (57.0) | 28 (59.6) | 123 (56.9) | 15 (62.5) | 106 (57.3) | 32 (58.2) | 102 (57.6) | 36 (57.1) | 110 (57.9) | 28 (56.0) |
AG | 91 (37.9) | 74 (38.3) | 17 (36.2) | 82 (38.0) | 9 (37.5) | 69 (37.3) | 22 (40.0) | 69 (39.0) | 22 (34.9) | 72 (37.9) | 19 (38.0) |
AA | 11 (4.6) | 9 (4.7) | 2 (4.3) | 11 (5.1) | 0 (0) | 10 (5.4) | 1 (1.8) | 6 (3.4) | 5 (7.9) | 8 (4.2) | 3 (6.0) |
p | 0.949 | 0.512 | 0.528 | 0.317 | 0.860 | ||||||
rs5845 | |||||||||||
GG | 145 (60.4) | 115 (59.6) | 30 (63.8) | 130 (60.2) | 15 (62.5) | 108 (58.4) | 37 (67.3) | 105 (59.3) | 40 (63.5) | 113 (59.5) | 32 (64.0) |
AG | 89 (37.1) | 73 (37.8) | 16 (34.0) | 80 (37.0) | 9 (37.5) | 71 (38.4) | 18 (32.7) | 69 (39.0) | 20 (31.7) | 74 (38.9) | 15 (30.0) |
AA | 6 (2.5) | 5 (2.6) | 1 (2.1) | 6 (2.8) | 0 (0) | 6 (3.2) | 0 (0) | 3 (1.7) | 3 (4.8) | 3 (1.6) | 3 (6.0) |
p | 0.291 | 0.687 | 0.259 | 0.281 | 0.130 | ||||||
SLC30A3 | |||||||||||
rs11126936 | |||||||||||
GG | 119 (49.6) | 99 (51.3) | 20 (42.6) | 109 (50.5) | 10 (41.7) | 89 (48.1) | 30 (54.5) | 86 (48.6) | 33 (52.4) | 99 (52.1) | 20 (40.0) |
GT | 92 (38.3) | 71 (36.8) | 21 (44.7) | 81 (37.5) | 11 (45.8) | 74 (40.0) | 18 (32.7) | 69 (39.0) | 23 (36.5) | 74 (38.9) | 18 (36.0) |
TT | 29 (12.1) | 23 (11.9) | 6 (12.8) | 26 (12.0) | 3 (12.5) | 22 (11.9) | 7 (12.7) | 22 (12.4) | 7 (11.1) | 17 (8.9) | 12 (24.0) |
p | 0.544 | 0.693 | 0.618 | 0.871 | 0.013* | ||||||
rs73924411 | |||||||||||
CC | 198 (82.5) | 160 (82.9) | 38 (80.9) | 181 (83.8) | 17 (70.8) | 156 (84.3) | 42 (76.4) | 150 (84.7) | 48 (76.2) | 154 (81.1) | 44 (88.0) |
CT | 41 (17.1) | 32 (16.6) | 9 (19.1) | 34 (15.7) | 7 (29.2) | 28 (15.1) | 13 (23.6) | 26 (14.7) | 15 (23.8) | 35 (18.4) | 6 (12.0) |
TT | 1 (0.4) | 1 (0.5) | 0 (0) | 1 (0.5) | 0 (0) | 1 (0.5) | 0 (0) | 1 (0.6) | 0 (0) | 1 (0.5) | 0 (0) |
p | 0.409 | 0.243 | 0.299 | 0.220 | 0.484 | ||||||