From: High-fat and obesogenic diets: current and future strategies to fight obesity and diabetes
Diet | Model | Effect | References |
---|---|---|---|
HFD | Rat | Hepatic insulin resistance | Samuel et al. (2004) |
 |  | Hepatic fat deposition |  |
MCD | Mouse | Proinflammatory gene expression | Lee et al. (2007) |
 |  | Hepatic steatosis |  |
HFD | Mouse | Hyperleptinemia | Wang et al. (2002) |
 |  | Decreased NPY gene expression |  |
MCD | Rat | High cholesterol in serum | Hussein et al. (2007) |
 |  | Hepatic steatosis |  |
HFD | Rat | Insulin resistance | Buettner et al. (2006) |
 |  | Pronounced obesity |  |
HFrD | Various | Insulin resistance | Basciano et al. (2005) |
 |  | Hypertriglyceridemia |  |
MCD | Mouse | Hepatic steatosis | Sahai et al. (2004) |
 |  | Increase in inflammatory factors expression |  |
MCD | Mouse | No obesity | Rinella and Green (2004) |
 |  | No insulin resistance |  |
MCD | Â | Hepatocellular damage | Pickens et al. (2010) |
+ HFrD | Â | Hepatic steatosis | Â |
CD | Rat | Hepatic steatosis | Fujita et al. (2010) |
 |  | Hepatic fibrosis |  |
CD | Rat | Hepatic mitochondrial dysfunction | Teodoro et al. (2008) |
 |  | Increased triglyceride hepatic deposition |  |
CDAA | Â | Heightened oxidative stress | Takeuchi-Yorimoto et al. (2013) |
 |  | Steatohepatitis |  |