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Fig. 5 | Genes & Nutrition

Fig. 5

From: Real-life use of vitamin D3-fortified bread and milk during a winter season: the effects of CYP2R1 and GC genes on 25-hydroxyvitamin D concentrations in Danish families, the VitmaD study

Fig. 5

The prevalence (%) of sufficient 25(OH)D concentrations, defined as >50 nmol/L, for each genetic risk score category stratified by quintile of total vitamin D intake at the end of the study. Total vitamin D intake was estimated as the sum of dietary vitamin D, use of multivitamin and vitamin D supplements and, for the fortification group, intake of vitamin D3-fortified bread and milk. The following quintile stratification was used: quintile 1: 0–2.9 μg/day; quintile 2: 3–7.4 μg/day; quintile 3: 7.5–9.9 μg/day; quintile 4: 10.0–14.9 μg/day; and quintile 5: >15.0 μg/day. Genetic risk score (range 0–8) was calculated as the sum of number of G-alleles of rs10741657, A-alleles of rs10766197, A-alleles of rs4588 and C/A-alleles of rs842999. Individuals carrying 0, 1 or 2 (0–2) risk alleles and individuals carrying 6, 7 or 8 (6–8) risk alleles were combined due to small sample size after quintile stratification by total vitamin D intake

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