Fig. 1From: The zinc matrix metalloproteinase ZMP-2 increases survival of Caenorhabditis elegans through interference with lipoprotein absorptionCholesterol transport is essential for the reduction of survival under heat stress by zmp-2 knockdown. RNAi versus vit-6 completely rescues the lifespan reduction which is due to zmp-2 RNAi in N2 wild-type nematodes (a). The functional loss of a receptor for receptor-mediated endocytosis in the rme-2 mutant prevented the toxicity mediated by zmp-2 RNAi in N2 completely (b)Back to article page