Fig. 4From: The zinc matrix metalloproteinase ZMP-2 increases survival of Caenorhabditis elegans through interference with lipoprotein absorptionDAF-16 mediates the detrimental effects of zmp-2 RNAi. When daf-16 was knocked down by RNAi, zmp-2 RNAi was no longer able to reduce the survival of wild-type C. elegans at 37 °C (a). DAF-16 was exclusively localized in the nuclei after zmp-2 RNAi as was evidenced using the transgenic strain TJ356 expressing DAF-16::GFP (b)Back to article page