Quercetin decreases high-fat diet induced body weight gain and accumulation of hepatic and circulating lipids in mice

Table 2 Top regulated genes from microarray analysis in liver with an absolute fold change >1.5 and p < 0.01

Gene symbol	Gene name	Accession number	Microarray		RT-qPCR
Gene symbol	Gene name	Accession number	FC	p	FC	p
Csad	Cysteine sulphinic acid decarboxylase	NM_144942	2.33	0.0045	2.73	0.001
Cib3	Calcium and integrin binding family member 3	NM_001080812	1.88	0.0004	n.a.
Fabp5	Fatty acid binding protein 5, epidermal	NM_010634	1.59	0.0075	1.37	0.173
Tfrc	Transferrin receptor	NM_011638	1.52	0.0069	1.45	0.016
Cyp3a59	Cytochrome P450, subfamily 3a59	NM_001105160	−1.51	0.0038	n.a.
Hao2	Hydroxyacid oxidase 2	NM_019545	−1.67	0.0022	−2.81	0.006
Cyp2b9	Cytochrome P450, family 2b9	NM_010000	−2.30	0.0009	−8.2	0.0003
Cyp2b13	Cytochrome P450, family 2b13	NM_007813	−2.39	0.0006	n.a.
Cyp2b10	Cytochrome P450, family 2b10	NM_009999	−2.63	0.0028	n.a.

Not assigned probes were not mentioned in the table; NAP111439-1 (FC = 1.64, p = 0.009), NAP114472-1 (FC = 1.59, p = 0.007), Gm10804 (FC = −1.83, p = 0.0069), A_55_P2071906 (FC = −1.9, p = 0.002). Fold changes are depicted as the expression values of quercetin over control animals. FC fold change, p p value; n.a. not assessed

ISSN: 1865-3499